Effect of Basal Testosterone and Dehydroepiandrosterone Sulphate Levels on in Vitro Fertilization Outcome in Normoresponders

İnci KAHYAOĞLU, Nafiye YILMAZ, Serkan KAHYAOĞLU, Ayten TÜRKKANI, Mahmut Nedim ÇİÇEK, Leyla MOLLAMAHMUTOĞLU

Ankara, Turkey

OBJECTIVE: The purpose of the present study is to evaluate the predictive value of basal total testosterone (total-T) and dehydroepiandrosterone sulphate (DHEAS) levels in normoresponder patients undergoing IVF-ET.
STUDY DESIGN: A total of 60 normoresponder infertile women, scheduled to undergo their first IVF/ET cycle were enrolled in this study. Day 2-4 basal concentrations of FSH, LH, E2, total testosterone, DHEAS and antral follicle count (AFC) were determined in preceding cycle.
RESULTS: No significant difference was found between pregnant and non-pregnant groups regarding the AFC, hormone and controlled ovarian hyperstimulation (COH) parameters (total dose of gonadotrophins (1995.7±851.1 vs 2296.4±845.3 IU), >14 mm follicles (9.3±3.1 vs 7.3±3.9), retrieved oocytes (12.4±5.1 vs 8.7±6.1) or number of good quality embryos (7.4±3.7 vs 4,4±3.6) (p>0.05). Testosterone and DHEAS was not correlated with COH parameters (p>0.05).
CONCLUSION: There is no correlation between testosterone and DHEAS levels and COH parameters in normoresponder IVF patients.
Key Words: Androgen, Normoresponder, In vitro fertilization



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