Uterine Serous Carcinoma Arising From Endometrial Polyp: A Case Report Sibel BEKTAŞ, Burak BAHADIR, Figen BARUT, Ülkü BAYAR, Şükrü Oğuz ÖZDAMAR Zonguldak, Turkey Serous carcinoma is the prototype of type II endometrial carcinoma. A 71-year-old woman who had history of smoking, diabetes mellitus and hypertension admitted to the hospital with postmenopausal uterine bleeding. Curettage material was diagnosed as adenocarcinoma. Hysterectomy specimen revealed a uterine polypoid mass which afterwards was histopathologically proven to be a serous carcinoma arising from an endometrial polyp. Immunohistochemically, tumor cells showed diffuse reaction for p53 and c-erbB-2, and focal reaction for estrogen and progesterone receptors. In addition to history of diabetes mellitus and hypertension, our case shared some clinical and immunohistochemical characteristics of type I endometrial carcinoma, such as focal expression of estrogen and progesterone receptors. Overexpressions of p53 and c-erbB-2 in this tumor type should be considered. Key Words: Serous carcinoma, Endometrial polyp, P53, C-erbB-2. Gynecol Obstet Rebrod Med;15:1 (57 - 60)
Uterine Serous Carcinoma Arising From Endometrial Polyp: A Case Report Sibel BEKTAŞ, Burak BAHADIR, Figen BARUT, Ülkü BAYAR, Şükrü Oğuz ÖZDAMAR Zonguldak, Turkey
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